Streamtuner2 used to run under Windows. Current versions should still, but aren't tested anymore.

• Simplest option to install it is per 0install feed:
  http://fossil.include-once.org/streamtuner2/doc/trunk/dev/0-st2.xml

  (Ought to work for Windows, MacOS, and BSD/Linux systems.)

Else it requires a working Python installation first. That includes Python with Gtk bindings, the requests and pyquery packages.

• The available .exe installer is really just a self-extracting ZIP. It'll unpack to Unix-style paths C:/usr/bin/ and C:/usr/share/streamtuner2.
  (The exe is actually more suitable now as raw zip/tarball, that just happens to have a wine GUI.)

• With the new .pyz package it's even easier to use however. So that's now the recommended approach. Simply start it with:

  python streamtuner2.pyz
  

  Or rename it to have a .pyzw extension, in case your setup already picks that up.

• In either case, you'll have to create a desktop shortcut yourself.

Streamtuner2 is primarily developed for BSD/Linux platforms. It's platform-agnostic through Python. On Windows there are enough alternatives already (more bling, mostly just limited in station sources), thus no significant userbase. Which is why this isn't considered a target.

There are probably modern Python distributions for Windows. No idea. It's definitely not something that should be handled on a per-application basis and with PyInstaller embellishments.